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Cholangitis is a condition in which inflammation of the bile ducts occurs, the channel that circulates bile from the liver to the intestine and gallbladder. Inflammation can cause swelling which ultimately disrupts the circulation system of bile, the fluid needed by the body to help the digestive process. Disrupted bile circulation system can cause symptoms such as fever, nausea, and abdominal pain.

Treatment of cholangitis will be better done immediately. Cholangitis that is ignored and does not get proper treatment can cause complications, such as kidney failure and even death.

Symptoms of Cholangitis

Symptoms that can be felt by cholangitis patients are abdominal pain. Pain itself has character and can appear in different locations. Pain that arises usually will feel like cramping or stabbing.

Apart from pain, people with cholangitis can also feel other symptoms, such as:

  • Fever.
  • Nausea.
  • Gag.
  • Jaundice (jaundice).

Causes of Cholangitis

Inflammation of the bile ducts experienced by people with cholangitis can be caused by many factors, but the most frequent is bacterial infection.

Some other factors that can cause cholangitis include:

  • Blood clots.
  • Tumor.
  • Parasitic infections.
  • Swelling of the pancreas.
  • Side effects of medical procedures, such as endoscopy.
  • Infection of the blood (bacteremia).


A person will be at higher risk of suffering from cholangitis if they are over 55 years of age or have a history of gallstones.

Cholangitis diagnosis

Diagnosis begins with examination of symptoms, medical history, and overall condition of the patient. After that, a series of tests can be done to ascertain the condition. Some of the tests used include:

  • Blood test.
  • Ultrasonography (USG).
  • MRI or CT scan.

In addition to the three tests above, there are also other methods commonly used to diagnose cholangitis, namely endoscopic retrograde cholangiopancreatography (ERCP) and percutaneous transhepatic cholangiography (PTCA). ERCP is a combination of X-ray imaging procedures with endoscopy, and PTCA is X-ray imaging that is assisted by injecting a contrast dye directly into the bile duct.

Cholangitis Treatment

Handling of cholangitis in each person is different, according to the underlying cause. If cholangitis is caused by a bacterial infection, treatment can be done by giving antibiotics. Some antibiotics commonly used to treat cholangitis include:

  • Ampicillin.
  • Piperasilin.
  • Metronidazole.
  • Quinolone, such as cipofloxacin and levofloxacin.


Cholangitis complications

Cholangitis that does not get proper treatment has the potential to cause other diseases and even death.

Some complications that can occur in people with cholangitis include:

  • Liver abscess.
  • Recurrence of cholangitis and lasts a long time.
  • Kidney failure.

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Generally skin cancer is caused by exposure to ultraviolet light which causes DNA damage to the skin tissue. The main source of ultraviolet light is sunlight which consists of three types, namely:
  • Ultraviolet A (UVA)
  • Ultraviolet B (UVB)
  • Ultraviolet C (UVC)
Of the three types of ultraviolet light, UVC is the most dangerous for the skin. But UVC rays can be absorbed by the atmosphere before reaching the ground. UVA and UVB can damage skin cells, especially pale ones, and potentially cause skin cancer.

Sources of artificial UV rays such as UV lamps and tanning beds can also cause skin cancer.

Some factors that can increase a person's risk of developing skin cancer are:

1. Have white skin. Everyone, regardless of skin color, can suffer from skin cancer. But white skin has a protection against weaker UV rays compared to darker skin. Darker skin has more amount of melanin so that it has more protection against UV rays. In addition, the easy formation of spots on the skin indicates that the skin is more susceptible to skin cancer.

2. Often exposed to sunlight. People who are often exposed to sunlight are more at risk of developing skin cancer than those who are rarely exposed to sunlight. Some conditions that can increase sun exposure include

  • Live in areas that have a sunny climate.
  • Living in a higher area.

3. Mole. People who have a lot of moles or have abnormal moles (larger than usual) are more at risk of developing skin cancer compared to people who have a little mole.

4. Age. People with advanced age are more susceptible to skin cancer than children or adolescents.

5. Skin that has sunburn. Blisters caused by sunlight make the skin more at risk of skin cancer, especially if the skin blisters occur when children or adolescents.

6. Actinic keratosis. In people with bright skin, easy exposure to sunlight causes the formation of patches of skin thickening on the face, hands and head. This condition is pre-cancerous, and has the potential to turn into skin cancer.

7. History of skin cancer. If someone has had skin cancer and recovered, there is a possibility that the same condition will reappear.

8. History of skin cancer in family members. Someone is at high risk of developing skin cancer if you have a sibling or parent who has had skin cancer.

9. Weakening the immune system. People with weakened immune systems have a high risk of developing skin cancer. Also included are people with HIV / AIDS, people taking immunosuppressant drugs, and organ transplant recipients.

10. Radiation therapy. Patients with eczema or zits given radiation therapy have a high risk of developing skin cancer, especially basal cell cancer.

11. Exposure to certain chemicals. Some carcinogenic chemicals, such as arsenic, can increase the risk of developing skin cancer.

Skin Cancer Diagnosis

To diagnose skin cancer accurately, the doctor will apply the following steps to the patient:

  • Physical examination of the skin. The doctor will examine the shape of the skin abnormality especially the changes that occur in physical appearance. With this examination, the doctor will determine whether the changes that occur are caused by cancer or other diseases.
  • Perform a skin biopsy. Examination of skin tissue samples taken by biopsy in the laboratory.


After the diagnosis is made, the doctor will determine the severity of skin cancer that is suffered based on the stage as follows:

  • Stage 0, indicates that the cancer tissue is still in the place where it first appeared and has not spread (in situ).
  • Stage 1, shows that the cancerous tissue is still small and has not spread.
  • Stage 2, shows that the cancerous tissue has grown, but has not spread.
  • Stage 3, shows that the cancer has enlarged and has spread to the surrounding tissue or to the closest lymph nodes.
  • Stage 4, indicates that the cancer has spread to other parts of the body or has undergone metastasis.


Staging of skin cancer is done to determine the right treatment. In basal cell carcinoma, cancer cells usually do not spread so that a skin biopsy can determine the type and stage of cancer. But in other types of skin cancer, such as squamous cell carcinoma, cell cell carcinoma, or melanoma, the doctor will do a follow-up examination to get more accurate results. One of the follow-up tests that is usually done is a lymph node biopsy in the cancer area.
"Situs ini dibuat dengan tujuan untuk membantu orang lain baik yang sedang menjual atau pun mencari rumah di Jepara dan sekitarnya seperti Demak, Kudus, Pati dan Semarang dan sekitarnya adapun data yang ada berasal dari group jual beli rumah seperti facebook, whatsapp atau yang lain. Harapan kami situs ini bisa menjadi sumber informasi yang bermanfaat" Rumah bukan hanya sekedar tempat untuk berteduh, rumah tempat kita berkumpul dengan keluarga yang kita cintai, tempat kita berbagi kebahagiaan dengan mereka. Oleh karena itu sebelum anda memutuskan untuk membeli sebuah rumah selain lokasi yang strategis, harga yang pas dengan keuangan anda, keamanan dan kenyamanan lingkungan rumah yang akan anda beli anda harus membicarakannya terlebih dahulu kepada keluarga anda. Dan jangan lupa untuk mencari informasi tips membeli rumah atau perumahan yang aman. "

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Mad cow is a disorder of the brain caused by prion infection (abnormal protein in livestock). Prions are found in many parts of the body of livestock, such as in the brain, eyes and spinal cord. If it attacks the brain, prions will develop and damage the nervous system.

In the world of medicine, mad cow disease in livestock is known as bovine spongiform encephalopathy (BSE). Whereas in humans, this disease is known as Creutzfeldt-Jakob disease (CJD), and is found in England, Scotland, Wales and Northern Ireland.

Creutzfeldt-Jakob disease (CJD) is a severe brain disorder that can cause fatal effects, even leading to death. The symptoms of this disease are generally similar to symptoms of dementia, Alzheimer's disease, and other brain disorders, but this infection is more aggressive and worsens in a short time.

Mad cow is relatively rare and rarely found. According to research, this disease attacks one in a million people per year and is found in many adults.

In general there are four types of Creutzfeldt-Jakob disease (CJD), namely:


  • Sporadic CJD. Is the type of mad cow disease that is most often found. Disorders occur as changes in brain protein into abnormal proteins, called prions. The cause is not known with certainty. Most diseases of this type occur in adults aged 45-75 years. Symptoms begin to develop at the age of 60-65 years.
  • Variant CJD (vCJD). Caused by consumption of livestock meat that is positively infected with mad cow disease and contains prions. The incubation period for this type of mad cow disease is very long, can be more than 10 years.
  • Familial CJD. Is the type of mad cow disease that is most rarely found. Someone suffers from this disorder because it is passed down in the family. This type attacks every one of the nine million people in the world.
  • Iatrogenic CJD. Accidentally transmitted through medical procedures such as medication and surgery. A number of non-sterilized medical equipment can be a medium for transmission of mad cow disease.


Symptoms of Mad Cow Disease

Most people with mad cow disease die within a year of the first symptoms appearing. Generally, mad cow disease is characterized by the appearance of several symptoms below:

  • Memory disorders and other brain functions.
  • Personality change.
  • Balance disorders.
  • Talk is unclear and vision is disturbed.
  • Experiencing psychological disorders such as anxiety depression.
  • Some parts of the body are tingling and difficult to move.
  • Having insomnia, dementia, and can continue to become coma.


If not handled properly, mad cow disease can cause complications in the brain. If that happens, someone will experience difficulties in thinking, remembering, isolating themselves from friends and family, and generally becoming indifferent to themselves. The most severe, this disease can cause death.

Causes of Mad Cow Disease

Until now it is not known what causes the change in normal proteins to prion proteins, which can occur in the brain, small intestine, or spinal cord of livestock. This disease can spread from one animal to another or even to humans.

Mad cow is transmitted when infected animals are slaughtered, then the body parts of infected animals are used for animal feed or human consumption. In other words, someone is at risk of contracting mad cow disease if they eat parts of the brain and spine of an infected animal.

Although the exact cause is unknown, genetic factors and age are believed to increase the risk of mad cow disease. Someone with familial CJD can reduce this condition to their offspring. In terms of age, people over the age of 60 are more prone to CJD sporadic.

Diagnosis of Mad Cow Disease

Allegations of mad cow disease are determined based on the development of symptoms and the patient's medical history. The only way to know for sure whether someone has mad cow disease is by brain biopsy through autopsy, which is done if the patient has died.

However, there are various diagnostic procedures that can help diagnose this disease, including:

  • Neurological examination. In the early stages, a neurologist (nerve specialist) will check for possible other diseases that have similar symptoms, such as Alzheimer's disease, Parkinson's disease, or brain tumors.
  • Electroencephalogram (EEG). To record brain activity and help detect abnormal electrical activity in CJD sporadic patients.
  • Scanning with MRI. Use radio waves and magnetic fields to get a detailed picture of the patient's brain condition.
  • Lumbar puncture. Retrieving cerebrospinal fluid samples from the patient's spine area for further investigation.
  • Genetic examination. A blood test is performed to detect the potential for mutations in the gene and ensure the existence of hereditary factors.
  • Tonsil biopsy. Taking tonsil tissue samples to see the possibility of prions in the tonsils of patients with CJD variants.


Treatment of Mad Cow Disease

There is no specific treatment that has been proven effective for treating mad cow disease. A number of drugs have been studied, but there is no real impact on healing this disease. Treatment with antivirals and antibiotics also does not have a positive influence on the patient's condition.

Treatment that can be given is drugs or medical measures to relieve symptoms that appear in patients. For example, giving an antidepressant to relieve psychological disorders or give clonazepam and sodium valproate to relieve muscle cramps.

Prevention of Mad Cow Disease

Mad cow often occurs spontaneously, making it difficult to prevent. Sterilization to prevent bacteria and viruses from spreading throughout the body is also ineffective. Even so, there are several efforts that can be done to reduce the risk of transmission of mad cow disease, including:

Destroying the source of infection. One way to minimize transmission of mad cow disease is to destroy meat carcasses that have the potential to transmit this disease, both to humans and other animals.
Safe blood transfusion. People who are at risk of contracting mad cow disease are prohibited from making blood donations to reduce the risk of transmission.
Limiting imported meat. Especially imported meat from countries prone to mad cow disease, such as Britain, Scotland, and Ireland.
Control of livestock. This method starts from controlling animal feed, treating sick animals, to limiting the consumption of livestock at risk of experiencing and transmitting mad cow disease.
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What is liver disease? Liver disease is a disease that must be watched out, given the importance of liver function in the body. The liver is the only organ in the body that can easily replace damaged cells, but if the cells needed are lost, the liver cannot possibly meet the body's needs.

The cause of chronic liver disease can come from infection by parasites and viruses. Until now there are 8 types of liver viruses. the most evil viruses are Hepatitis B (HVB) and Hepatitis C (HCV) viruses. While the tip of hepatitis is cirrhosis. Liver cirrhosis cells turn into connective tissue can not recover or normal again, so the function decreases. Another case if the cirrhosis in all parts of the liver can cause the liver to become paralyzed and end with liver failure.

Symptoms of Liver Disease

Get to know the symptoms of the liver so you can immediately visit a doctor before the symptoms of this liver disease become more severe. In addition to decreased liver function, almost all liver inflammation causes symptoms that look like jaundice. This depends on the cause, symptoms and signs of participation that are not the same.

If caused by an infection, liver symptoms will definitely be accompanied by fever, headache. lethargic, and weak. In addition, the elimination of nausea and vomiting also always accompanies the symptoms of this liver disease. When observed, the skin and the white part of the eye will appear yellow, as well as the urine which will turn to color like tea.

In addition to all the symptoms of the liver above, there is usually a feeling of discomfort in the right upper abdomen and pain when pressed. One thing that must be considered, that not all diseases in the liver will cause yellow symptoms on the skin and the white part of the eye.

Causes of Liver Disease

There are various liver diseases that can attack at any time. Recorded more than 100 liver diseases with symptoms of liver disease and different causes of liver disease. The following are the causes of liver pain that you need to know;


  • Alcohol consumption
  • Obesity
  • Exposure to certain chemicals
  • The use of drugs can be a cause of liver disease
  • Having free sex
  • Diabetes


Prevention of Chronic Liver Disease

Don't ignore the importance of maintaining liver health so that you don't experience chronic liver disease. According to liver disease specialists, to prevent the emergence and development of liver disease, you must meet several recommendations from these Methods Of Healing to ensure a healthier lifestyle, namely:

Avoid alcohol consumption

The liver functions to filter toxins from the body. But, this liver function can be disrupted if you consume alcohol, especially in large quantities. So, stop consuming alcohol if you want your liver to be healthy.

Limit consumption of high-fat foods

Avoid fast food to keep the liver in good condition. Regular weight control, because obesity, like diabetes, can be a trigger for liver disease. Watch your food, don't eat food carelessly. This can reduce liver function through the accumulation of toxins and fats in the body.

Don't linger in a toxic environment

The liver filters substances harmful to the body. However, if the capacity is full, then the heart cannot function to become a filter. Reduce exposure to common pollutants such as cigarette smoke or paint fumes

Follow the rules of clean living

Diligently wash your hands, especially before eating and after eating or after from the toilet. Do not drink water from equipment used by strangers, before actually washing it properly.

Protect yourself against liver viruses

To avoid contact with liver viruses, you must take certain steps to protect yourself from infected objects: safe sex, avoid tattoos, and use injecting drugs.

Regular health checks

Often chronic liver disease is found accidentally or when you examine other diseases. You are recommended to do a laboratory examination every year to determine the condition of the liver while detecting early stages of liver disease.

How to treat liver disease

You need to understand the symptoms of the liver and its treatment. Diseases that attack the liver, especially the type of Hepatitis A generally can heal itself without administration of drugs. Only adequate rest is needed. As with Hepatitis B and C, which requires treatment to be cured. Usually the doctor will give an injection of interferon (interferon Alpha) for 6-12 months. In Hepatitis B, interferon administration will be better if the results are combined with Lamivudine (virus suppressor) or with Famciclovir. As for Hepatitis C, interferon is combined with Ribavirin.

Besides knowing about liver disease and its treatment, you also know that liver disease is contagious, though not all of them. Which determines whether or not liver disease is a cause of the disease itself. If chronic liver disease is caused by lifestyle, then the disease is not a contagious liver disease. However, if the disease is a disease of the liver caused by a viral infection, then liver disease is contagious.

The method of transmission is to live together, share personal items, consume food contaminated with stool containing viruses, have sex with patients, receive blood transfusions from patients, and use needles that have been exposed to hepatitis viruses that cause chronic liver disease.
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